LVIP01-SD1-1
The cell line is not submitted yet.
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General
Cell Line |
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| hPSCreg name | LVPEIi007-A |
| Cite as: | LVPEIi007-A (RRID:CVCL_D6MV) |
| Alternative name(s) |
LVIP01-SD1-1
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| Cell line type | Human induced pluripotent stem cell (hiPSC) |
| Similar lines | No similar lines found. |
| Last update | 3rd April 2024 |
| Notes | This is an autosomal recessive retinal dystrophy (ARRD) patient-specific, induced pluripotent stem cell line, carrying a homozygous point mutation within exon 44 of ABCA4 leading to Arg2030Ter. This mutation (c.6088C>T) results in premature truncation of the protein lacking C-terminal nucleotide binding domain. This line was generated using retroviral vectors encoding hOCT3/4, hSOX2, hKLF4 and hcMYC transgenes. This line has been stably maintained beyond passage 20, expresses the endogenous stem cell markers such as, OCT4, SOX2, NANOG, SSEA4 and exhibits a normal karyotype, forms teratomas comprising of all three lineage cells. |
| User feedback | |
Provider |
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| Generator |
L.V. Prasad Eye Institute (LVPEI)
Contact:
L.V. Prasad Eye Institute (LVPEI) |
| Owner | L.V. Prasad Eye Institute (LVPEI) |
| Distributors | |
External Databases |
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| BioSamples | SAMEA115082726 |
| Cellosaurus | CVCL_D6MV |
| Wikidata | Q127382714 |
General Information |
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| Publications | |
| * Is the cell line readily obtainable for third parties? |
Yes Research use: allowed
Clinical use: not allowed
Commercial use: allowed
Additional restrictions:
Terms and conditions apply for commercial use |
hIPSC Derivation
General |
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