MHHi017-A

Registration Summary:

A P E C

PCD-P2_DNAH5 clone 22

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	MHHi017-A
Cite as:	MHHi017-A (RRID:CVCL_ZJ18)
Alternative name(s)	PCD-P2_DNAH5 clone 22
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	18th November 2019
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Provider
Generator	Hannover Medical School (MHH)
External Databases
Cellosaurus	CVCL_ZJ18
Wikidata	Q98127237
General Information
Publications	Drick N et al. Generation of two human induced pluripotent stem cell lines (MHHi017-A, MHHi017-B) from a patient with primary ciliary dyskinesia carrying a homozygous mutation (c.7915C > T [p.Arg2639*]) in the DNAH5 gene. Stem cell research. 2020 Jul;46:101848. Yang W et al. Multiomics Analysis of a DNAH5-Mutated PCD Organoid Model Revealed the Key Role of the TGF-β/BMP and Notch Pathways in Epithelial Differentiation and the Immune Response in DNAH5-Mutated Patients. Cells. 2022 Dec 12;11(24). von Schledorn L et al. Primary Ciliary Dyskinesia Patient-Specific hiPSC-Derived Airway Epithelium in Air-Liquid Interface Culture Recapitulates Disease Specific Phenotypes In Vitro. Cells. 2023 May 24;12(11).

hIPSC Derivation

General