MHHi017-B

Registration Summary:

A P E C

PCD-P2_DNAH5 clone 24

The cell line is not submitted yet.

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General

Cell Line
hPSCreg Name	MHHi017-B
Alternative name(s)	PCD-P2_DNAH5 clone 24
Cell line type	Human induced pluripotent stem cell (hiPSC)
Last update	18th November 2019
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Provider
Generator	Hannover Medical School (MHH)
External Databases
Cellosaurus	CVCL_ZJ19
Wikidata	Q98127238
General Information
Publications	Drick N et al. Generation of two human induced pluripotent stem cell lines (MHHi017-A, MHHi017-B) from a patient with primary ciliary dyskinesia carrying a homozygous mutation (c.7915C > T [p.Arg2639*]) in the DNAH5 gene. Stem cell research. 2020 Jul;46:101848. Yang W et al. Multiomics Analysis of a DNAH5-Mutated PCD Organoid Model Revealed the Key Role of the TGF-β/BMP and Notch Pathways in Epithelial Differentiation and the Immune Response in DNAH5-Mutated Patients. Cells. 2022 Dec 12;11(24).

hIPSC Derivation

General