NIHTVBi004-A

Registration Summary:

A P E C

HT405A

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	NIHTVBi004-A
Cite as:	NIHTVBi004-A (RRID:CVCL_ZE05)
Alternative name(s)	HT405A
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	5th March 2019
User feedback	Written by on No feedback available yet. Login to share your feedback, experiences or results with the research community.
Provider
Generator	National Institutes of Health-National Heart, Lung, and Blood Institute (NIHTVB)
External iPSC Databases
Cellosaurus	CVCL_ZE05
Wikidata	Q98127867
General iPSC Information
Publications	Chen G et al. Generation of human induced pluripotent stem cells (NIHTVBi004-A, NIHTVBi005-A, NIHTVBi006-A, NIHTVBi007-A, NIHTVBi008-A) from 5 CADASIL patients with NOTCH3 mutation. Stem cell research. 2020 May;45:101821. Harper RL et al. Development of vascular disease models to explore disease causation and pathomechanisms of rare vascular diseases. Seminars in immunopathology. 2022 May;44(3):259-268. Bugallo-Casal Ana et al. NOTCH3 Variant Position Affects the Phenotype at the Pluripotent Stem Cell Level in CADASIL. NeuroMolecular Medicine. 2025-02-27. Sun Ruihua et al. NOTCH3 signal activation by its extracellular domain accumulation in an iPSC line newly established from a CADASIL patient. Human Cell. 2026-05-24.

iPSC Derivation

General