NIHTVBi005-A

Registration Summary:

A P E C

HT406D

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	NIHTVBi005-A
Cite as:	NIHTVBi005-A (RRID:CVCL_ZE06)
Alternative name(s)	HT406D
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	5th March 2019
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Provider
Generator	National Institutes of Health-National Heart, Lung, and Blood Institute (NIHTVB)
External iPSC Databases
Cellosaurus	CVCL_ZE06
Wikidata	Q98127869
General iPSC Information
Publications	Chen G et al. Generation of human induced pluripotent stem cells (NIHTVBi004-A, NIHTVBi005-A, NIHTVBi006-A, NIHTVBi007-A, NIHTVBi008-A) from 5 CADASIL patients with NOTCH3 mutation. Stem cell research. 2020 May;45:101821. Harper RL et al. Development of vascular disease models to explore disease causation and pathomechanisms of rare vascular diseases. Seminars in immunopathology. 2022 May;44(3):259-268. Bugallo-Casal Ana et al. NOTCH3 Variant Position Affects the Phenotype at the Pluripotent Stem Cell Level in CADASIL. NeuroMolecular Medicine. 2025-02-27. Sun Ruihua et al. NOTCH3 signal activation by its extracellular domain accumulation in an iPSC line newly established from a CADASIL patient. Human Cell. 2026-05-24.

iPSC Derivation

General