General

Cell Line
hPSCreg name	NIMHi001-A-1
Cite as: When citing this cell line, please use the hPSCreg name (see Naming Tool ) and the corresponding Research Resource ID (RRID).	NIMHi001-A-1
Alternative name(s)	PD01 Isogenic
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	25th April 2026
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Provider
Generator	National Institute of Mental Health and Neurosciences (NIMH) Contact: National Institute of Mental Health and Neurosciences (NIMH)
Owner	National Institute of Mental Health and Neurosciences (NIMH)
Distributors	National Institute of Mental Health and Neurosciences (NIMH)
Derivation country	India
External Databases
BioSamples	SAMEA122228491
General Information
* Is the cell line readily obtainable for third parties?	No
Subclone of	NIMHi001-A

Donor Information

General Donor Information
Sex	male
Ethnicity	Asian Indian
Phenotype and Disease related information (Donor)
Diseases	A disease was diagnosed. Obsolete_Parkinson's disease The donor is a carrier of a disease-associated mutation and affected. Synonyms Parkinson's syndrome Parkinsons Primary Parkinsonism Parkinsons disease Parkinson disease Parkinson's disease (disorder) Parkinson's disease NOS Parkinson Disease, Idiopathic PARKINSON DIS IDIOPATHIC PARKINSONS DIS PARKINSON DIS IDIOPATHIC Parkinsonism, Primary Parkinson's Disease, Lewy Body IDIOPATHIC PARKINSON DIS Idiopathic PD Idiopathic Parkinson Disease Lewy Body Parkinson's Disease Parkinsonian disorder LEWY BODY PARKINSON DIS Parkinson's Idiopathic Parkinson's Disease Parkinson's disease NOS (disorder) Lewy Body Parkinson Disease PARKINSONS DIS IDIOPATHIC PARKINSONS DIS Parkinson's Disease, Idiopathic Parkinson syndrome PARKINSONS DIS LEWY BODY Paralysis agitans show more synonyms show less synonyms
Family history	Not known
Is the medical history available upon request?	No
Is clinical information available?	Yes
External Databases (Donor)
BioSamples	SAMEA6675832

Ethics

Also have a look at the ethics information for the parental line NIMHi001-A .

Is there an MTA available for the cell line?	No
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?	Thermo Fisher Scientific
Are you aware of any constraints on the use or distribution of the cell line from the owner or any parties identified in the query above?	No

hIPSC Derivation

General
The source cell information can be found in the parental cell line NIMHi001-A.
Passage number reprogrammed	9
Reprogramming method
Vector free reprogramming
Other
Derived under xeno-free conditions	Unknown
Derived under GMP?	Unknown
Available as clinical grade?	Unknown

Culture Conditions

Characterisation

No characterisation data could be found for this subclone. Please open parental cell line NIMHi001-A .

Genotyping

Karyotyping (Cell Line)

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications

Parkinson Disease Synonyms Parkinson Disease Parkinson's disease Parkinson's Disease Genetic modifications LRRK2 (target) Type of modification Isogenic modification Chromosome location 12q.12 Nucleotide sequence variant in HGVS format NM_198578.4:c.4111G>A Protein sequence variant in HGVS format NP_940980.4:p.Val1371Ile Is the modification homozygous or heterozygous? Homozygous How has the target locus been modified? Repaired