OSRi011-A-1

Iso SNCA

The cell line is not validated yet.

General

iPSC Line

hPSCreg name OSRi011-A-1
Cite as:
OSRi011-A-1
Alternative name(s)
Iso SNCA
iPSC line type Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines
OSRi011-A
(4xSNCA)
Donor diseases:
parkinsonian disorder
BIONi010-C-24
(BIONi010-C Dox a-syn)
Last update 23rd September 2025
User feedback
No feedback available yet.

Login to share your feedback, experiences or results with the research community.

Provider

Generator Ospedale San Raffaele (OSR)
Owner Ospedale San Raffaele (OSR)
Distributors
Derivation country Italy

External iPSC Databases

General iPSC Information

Projects
* Is the cell line readily obtainable for third parties?
No
Subclone of

iPSC Genetic Modification

Genetic modifications not related to a disease
SNCA (target)
Isogenic modification

Donor Information

General Donor Information

Sex female
Ethnicity Caucasic

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.

Ethics

Also have a look at the ethics information for the parental line OSRi011-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

iPSC Derivation

General

The source cell information can be found in the parental cell line OSRi011-A.

Reprogramming method

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

iPSC Culture Conditions

Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzymatically
Accutase
O2 Concentration 20 %
CO2 Concentration 5 %
Medium mTeSR™ 1
Has Rock inhibitor (Y27632) been used at passage previously with this iPSC line?
Yes
Has Rock inhibitor (Y27632) been used at cryo previously with this iPSC line?
Yes
Has Rock inhibitor (Y27632) been used at thaw previously with this iPSC line?
Yes

iPSC Characterisation

Microbiology / Virus Screening

Mycoplasma Negative

Genotyping

Karyotyping (iPSC Line)

Has the iPSC line karyotype been analysed?
Yes
46,XX
Passage number: 20

Other Genotyping (iPSC Line)