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SCVIi190-A

Registration Summary:
The cell line is not validated yet.
SCVIi190-A

General

iPSC Line
hPSCreg name SCVIi190-A
Cite as:
SCVIi190-A
iPSC line type Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines No similar lines found.
Last update 9th July 2026
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Provider
Generator Stanford Cardiovascular Institute (SCVI)
Owner Stanford Cardiovascular Institute (SCVI)
Distributors
Derivation country United States

General iPSC Information
* Is the cell line readily obtainable for third parties?
No

Donor Information

General Donor Information
Sex male
Ethnicity White not Hispanic or Latino

Phenotype and Disease related information (Donor)
Diseases A disease was diagnosed.
DiGeorge syndrome
The donor is a carrier of a disease-associated mutation and affected.
Synonyms
  • 22q deletion syndrome(s)
  • 22q11.2 deletion syndrome
  • Shprintzen syndrome
  • Sphrintzen
  • DGS
  • DGS1
  • Di-George syndrome
  • DiGeorge anomaly
  • DiGeorge syndrome type 1
  • DiGeorge syndrome
  • DiGeorge's syndrome
  • VCF
  • pharyngeal pouch syndrome
show more synonyms

Karyotyping (Donor)
Has the donor karyotype been analysed?
Yes
46,XY

Other Genotyping (Donor)
Is there genome-wide genotyping or functional data available?
Yes

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? Yes
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
* Does consent expressly prevent the derivation of pluripotent stem cells? No
* Does consent pertain to a specific research project? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No

Does consent permit research by

an academic institution? Yes
a public organisation? No
a non-profit company? No
a for-profit corporation? No
How may genetic information associated with the cell line be accessed? Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? Stanford IRB committee
Approval number 29904
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

iPSC Derivation

General
Source cell line name Derived Peripheral Blood Mononuclear Cell
Source cell type
Peripheral Blood Mononuclear Cell
A peripheral blood cell with a single nucleus. This category includes lymphocytes and monocytes.
Synonyms
  • PERIPHERAL BLOOD MONONUCLEAR CELL
  • Peripheral Blood Mononuclear Cell
  • PBMC
Source cell origin
Blood
A liquid tissue; its major function is to transport oxygen throughout the body. It also supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection. Several hormones also travel in the blood.
Synonyms
  • Reticuloendothelial System, Blood
  • Peripheral Blood
  • peripheral blood
  • blood
  • Blood
  • Whole Blood
  • BLOOD
  • portion of blood
  • vertebrate blood
show more synonyms

Reprogramming method
Vector type Non-integrating
Vector Sendai virus
Is reprogramming vector detectable?
No
Methods used
RT-PCR

Vector free reprogramming

Other
Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

iPSC Culture Conditions

Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzyme-free cell dissociation
EDTA
O2 Concentration 20 %
CO2 Concentration 5 %
Medium Essential 8™
Has Rock inhibitor (Y27632) been used at passage previously with this iPSC line?
Yes
Has Rock inhibitor (Y27632) been used at cryo previously with this iPSC line?
No
Has Rock inhibitor (Y27632) been used at thaw previously with this iPSC line?
Yes

iPSC Characterisation

Analysis of undifferentiated iPSCs
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
SOX2
Yes
NANOG
Yes
Morphology pictures

Genotyping

Karyotyping (iPSC Line)
Has the iPSC line karyotype been analysed?
Yes
46,XY
Passage number: P12

Other Genotyping (iPSC Line)