General

iPSC Line
hPSCreg name	SCVIi191-A
Cite as: When citing this cell line, please use the hPSCreg name (see Naming Tool ) and the corresponding Research Resource ID (RRID).	SCVIi191-A
Alternative name(s)	SCVI3162
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	9th July 2026
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Provider
Generator	Stanford Cardiovascular Institute (SCVI) Contact: Stanford Cardiovascular Institute (SCVI)
Owner	Stanford Cardiovascular Institute (SCVI)
Distributors	Stanford Cardiovascular Institute (SCVI)
Derivation country	United States
General iPSC Information
* Is the cell line readily obtainable for third parties?	No

Donor Information

General Donor Information
Sex	female
Phenotype and Disease related information (Donor)
Diseases	A disease was diagnosed. DiGeorge syndrome Synonyms 22q deletion syndrome(s) 22q11.2 deletion syndrome Shprintzen syndrome Sphrintzen DGS DGS1 Di-George syndrome DiGeorge anomaly DiGeorge syndrome type 1 DiGeorge syndrome DiGeorge's syndrome VCF pharyngeal pouch syndrome show more synonyms show less synonyms
Karyotyping (Donor)
Has the donor karyotype been analysed?	Yes 46,XX
Other Genotyping (Donor)
Is there genome-wide genotyping or functional data available?	Yes

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived?	Yes
Was the consent voluntarily given?	Yes
Has the donor been informed that participation will not directly influence their personal treatment?	Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor?	Yes
Do you (Depositor/Provider) hold the original Donor Consent Form?	No
If you do not hold the Donor Consent Form, do you know who does?	Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised.	anonymised
Does consent explicitly allow the derivation of pluripotent stem cells?	Yes
* Does consent expressly prevent the derivation of pluripotent stem cells?	No
* Does consent pertain to a specific research project?	No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world?	No
Does consent permit research by
an academic institution?	Yes
a public organisation?	No
a non-profit company?	No
a for-profit corporation?	No
How may genetic information associated with the cell line be accessed?	Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample?	No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions?	Yes
Name of accrediting authority involved?	Stanford IRB committee
Approval number	29904
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

iPSC Derivation

General
Source cell line name	Derived Peripheral Blood Mononuclear Cell Derived from same source line (potentially other lot and donor, see below): CBDTi001-A AUMCi002-A AUMCi003-A AUMCi004-A AUMCi005-A AUMCi006-A AUMCi007-A AUMCi008-A AUMCi009-A SCVIi152-A SCVIi153-A SCVIi186-A SCVIi187-A SCVIi190-A
Source cell type	Peripheral Blood Mononuclear Cell A peripheral blood cell with a single nucleus. This category includes lymphocytes and monocytes. Synonyms PERIPHERAL BLOOD MONONUCLEAR CELL Peripheral Blood Mononuclear Cell PBMC
Source cell origin	Blood A liquid tissue; its major function is to transport oxygen throughout the body. It also supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection. Several hormones also travel in the blood. Synonyms Reticuloendothelial System, Blood Peripheral Blood peripheral blood blood Blood Whole Blood BLOOD portion of blood vertebrate blood show more synonyms show less synonyms
Reprogramming method
Vector type	Non-integrating
Vector	Sendai virus
Is reprogramming vector detectable?	No
Methods used	RT-PCR
Vector free reprogramming
Other
Derived under xeno-free conditions	Unknown
Derived under GMP?	Unknown
Available as clinical grade?	Unknown

iPSC Culture Conditions

Surface coating	Matrigel/Geltrex
Feeder cells	No
Passage method	Enzyme-free cell dissociation EDTA
O2 Concentration	20 %
CO2 Concentration	5 %
Medium	Essential 8™
Has Rock inhibitor (Y27632) been used at passage previously with this iPSC line?	Yes
Has Rock inhibitor (Y27632) been used at cryo previously with this iPSC line?	No
Has Rock inhibitor (Y27632) been used at thaw previously with this iPSC line?	Yes

iPSC Characterisation

Analysis of undifferentiated iPSCs

Morphology

Morphology pictures

Genotyping

Karyotyping (iPSC Line)
Has the iPSC line karyotype been analysed?	Yes 46,XX Passage number: p12
Other Genotyping (iPSC Line)