TRNDi003-A

Registration Summary:

A P E C

iPSC HT215A

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	TRNDi003-A
Cite as:	TRNDi003-A (RRID:CVCL_UL12)
Alternative name(s)	iPSC HT215A
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	27th March 2019
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Provider
Generator	NIH/NCATS-TRND Branch (TRND)
External Databases
Cellosaurus	CVCL_UL12
Wikidata	Q98133577
General Information
Publications	Li R et al. Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene. Stem cell research. 2019 Jan;34:101374. Brodehl A et al. Human Induced Pluripotent Stem-Cell-Derived Cardiomyocytes as Models for Genetic Cardiomyopathies. International journal of molecular sciences. 2019 Sep 6;20(18). Gripp KW et al. The sixth international RASopathies symposium: Precision medicine-From promise to practice. American journal of medical genetics. Part A. 2020 Mar;182(3):597-606. Panda A et al. Non-viral reprogramming and induced pluripotent stem cells for cardiovascular therapy. Differentiation; research in biological diversity. 2020 Mar-Apr;112:58-66. Liu WS et al. Investigating the reason for loss-of-function of Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) caused by Y279C mutation through molecular dynamics simulation. Journal of biomolecular structure & dynamics. 2020 Jun;38(9):2509-2520. Bekhite MM et al. Human Induced Pluripotent Stem Cell as a Disease Modeling and Drug Development Platform-A Cardiac Perspective. Cells. 2021 Dec 9;10(12). Ercan-Sencicek A. Gulhan et al. Induced pluripotent stem cells for modeling Noonan, Noonan Syndrome with Multiple Lentigines, and Costello Syndromes. Current Progress in iPSC Disease Modeling. 2022-00-00. Solman M et al. Modeling (not so) rare developmental disorders associated with mutations in the protein-tyrosine phosphatase SHP2. Frontiers in cell and developmental biology. 2022;10:1046415. Bajia D et al. Effects of Noonan Syndrome-Germline Mutations on Mitochondria and Energy Metabolism. Cells. 2022 Oct 1;11(19).

hIPSC Derivation

General