UEFi003-A

Registration Summary:

A P E C

MADGIC 12B

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	UEFi003-A
Cite as:	UEFi003-A (RRID:CVCL_A9QA)
Alternative name(s)	MADGIC 12B
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	25th January 2023
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Provider
Generator	University of Eastern Finland (UEF)
External Databases
Cellosaurus	CVCL_A9QA
Wikidata	Q102115053
General Information
Publications	Rolova T et al. Generation of a human induced pluripotent stem cell line (UEFi003-A) carrying heterozygous A673T variant in amyloid precursor protein associated with a reduced risk of Alzheimer's disease. Stem cell research. 2020 Oct;48:101968. Xia Q et al. The Protective A673T Mutation of Amyloid Precursor Protein (APP) in Alzheimer's Disease. Molecular neurobiology. 2021 Aug;58(8):4038-4050. Catania M et al. A novel bio-inspired strategy to prevent amyloidogenesis and synaptic damage in Alzheimer's disease. Molecular psychiatry. 2022 Dec;27(12):5227-5234. Kettunen Pinja et al. SARS-CoV-2 Infection of Human Neurons Is TMPRSS2 Independent, Requires Endosomal Cell Entry, and Can Be Blocked by Inhibitors of Host Phosphoinositol-5 Kinase. Journal of Virology. 2023-04-27.

hIPSC Derivation

General