UNIBSi017-A

EDS-iPSC

The cell line is not validated yet.

General

Cell Line

hPSCreg Name
UNIBSi017-A
Alternative name(s)
EDS-iPSC
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 9th June 2022
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Provider

Generator University of Brescia (UNIBS)

External Databases

BioSamples SAMEA14099154

General Information

Publications
* Is the cell line readily obtainable for third parties?
No

Donor Information

General Donor Information

Sex female

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Cardiospondylofacial syndrome
The donor is a carrier of a disease-associated mutation and affected.

External Databases (Donor)

BioSamples SAMEA14099155

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? No
Provide contact information of the holder of the original Donor Information Sheet: Lucia Micale (l.micale@operapadrepio.it)
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? Yes
Contact information / weblink Lucia Micale (l.micale@operapadrepio.it)
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed? Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? Institutional Review Board of Fondazione IRCCS-Casa Sollievo della Sofferenza
Approval number 2021/13/CE
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell line name EDS1331
Source cell type
dermal fibroblast
Dermal fibroblasts are the major cell type in dermis and are commonly accepted as terminally differentiated cells.
Source cell origin
Muscle of arm
Synonyms
  • Arm muscle

Reprogramming method

Vector type Non-integrating
Vector Sendai virus
Is reprogramming vector detectable?
No
Methods used
PCR

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium mTeSR™ 1

Characterisation

No characterisation data could be found.

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
45, XX rob(13;14)(q10;q10)

Other Genotyping (Cell Line)