USTCi001-A-1

Registration Summary:

A P E C

The cell line is not submitted yet.

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General

Cell Line
hPSCreg name	USTCi001-A-1
Cite as:	USTCi001-A-1 (RRID:CVCL_ZU60)
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	10th June 2020
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Provider
Generator	School of Life Sciences, University of Science and Technology of China (USTC)
External Databases
Cellosaurus	CVCL_ZU60
Wikidata	Q98134374
General Information
Publications	Zhao H et al. Generation of corrected-hiPSC (USTCi001-A-1) from epilepsy patient iPSCs using TALEN-mediated editing of the SCN1A gene. Stem cell research. 2020 Jul;46:101864. Zhao H et al. A heterozygous SCN1A (c.A5768G/+) mutant human induced pluripotent stem cell line (USTCi002-A) generated using TALEN-mediated precise gene editing. Stem cell research. 2020 Dec;49:102058. Khorkova O et al. Nucleic Acid-Based Therapeutics in Orphan Neurological Disorders: Recent Developments. Frontiers in molecular biosciences. 2021;8:643681. Tahbaz M et al. Immune Protection of Stem Cell-Derived Islet Cell Therapy for Treating Diabetes. Frontiers in endocrinology. 2021;12:716625. Zayat V et al. Concise Review: Stem Cell Models of SCN1A-Related Encephalopathies-Current Perspective and Future Therapies. Cells. 2022 Oct 4;11(19). Javaid MS et al. Human In Vitro Models of Epilepsy Using Embryonic and Induced Pluripotent Stem Cells. Cells. 2022 Dec 7;11(24). Sharma Rakesh. Innovative Genoceuticals in Human Gene Therapy Solutions: Challenges and Safe Clinical Trials of Orphan Gene Therapy Products. Current Gene Therapy. 2024-02-00. Gao Jingjing et al. Gene therapy for CNS disorders: modalities, delivery and translational challenges. Nature Reviews Neuroscience. 2024-08-00.
Subclone of	USTCi001-A

hIPSC Derivation

General
The source cell information can be found in the parental cell line USTCi001-A.