USTCi001-A-1

iPSC Line

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External iPSC Databases

General iPSC Information

• Zhao H et al. Generation of corrected-hiPSC (USTCi001-A-1) from epilepsy patient iPSCs using TALEN-mediated editing of the SCN1A gene. Stem cell research. 2020 Jul;46:101864.
• Zhao H et al. A heterozygous SCN1A (c.A5768G/+) mutant human induced pluripotent stem cell line (USTCi002-A) generated using TALEN-mediated precise gene editing. Stem cell research. 2020 Dec;49:102058.
• Khorkova O et al. Nucleic Acid-Based Therapeutics in Orphan Neurological Disorders: Recent Developments. Frontiers in molecular biosciences. 2021;8:643681.
• Tahbaz M et al. Immune Protection of Stem Cell-Derived Islet Cell Therapy for Treating Diabetes. Frontiers in endocrinology. 2021;12:716625.
• Zayat V et al. Concise Review: Stem Cell Models of SCN1A-Related Encephalopathies-Current Perspective and Future Therapies. Cells. 2022 Oct 4;11(19).
• Javaid MS et al. Human In Vitro Models of Epilepsy Using Embryonic and Induced Pluripotent Stem Cells. Cells. 2022 Dec 7;11(24).
• Sharma Rakesh. Innovative Genoceuticals in Human Gene Therapy Solutions: Challenges and Safe Clinical Trials of Orphan Gene Therapy Products. Current Gene Therapy. 2024-02-00.
• Gao Jingjing et al. Gene therapy for CNS disorders: modalities, delivery and translational challenges. Nature Reviews Neuroscience. 2024-08-00.
• Khatun Munzura et al. Isolation, Purification, and Characterization of Endochitinase Producing Bacteria as Potential Bio-control Agents of Fungal Phytopathogens. Natural Product Communications. 2025-06-00.
• Hamed Munerah. Advancements in Stem Cell Therapy for Managing Drug-Resistant Epilepsy. Molecular Neurobiology. 2026-01-00.

• USTCi001-A

General