A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability
Summary
This efficient and cost-effective universal system for cardiac differentiation of hiPSC allows a potentially unlimited production of functional cardiomyocytes suitable for application to hPSC-based drug development, cardiac disease modeling, and the future generation of clinically-safe nonviral human cardiac cells for regenerative medicine.
Authors | Burridge PW, Thompson S, Millrod MA, Weinberg S, Yuan X, Peters A, Mahairaki V, Koliatsos VE, Tung L, Zambidis ET |
---|---|
Journal | PloS one |
Publication Date | 2011 Apr 8;6(4):e18293 |
PubMed | 21494607 |
PubMed Central | PMC3072973 |
DOI | 10.1371/journal.pone.0018293 |