A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability

Summary

This efficient and cost-effective universal system for cardiac differentiation of hiPSC allows a potentially unlimited production of functional cardiomyocytes suitable for application to hPSC-based drug development, cardiac disease modeling, and the future generation of clinically-safe nonviral human cardiac cells for regenerative medicine.

Authors Burridge PW, Thompson S, Millrod MA, Weinberg S, Yuan X, Peters A, Mahairaki V, Koliatsos VE, Tung L, Zambidis ET
Journal PloS one
Publication Date 2011 Apr 8;6(4):e18293
PubMed 21494607
PubMed Central PMC3072973
DOI 10.1371/journal.pone.0018293

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