A novel approach for studying mast cell-driven disorders: Mast cells derived from induced pluripotent stem cells
Summary
This novel hiPSC-based approach provides a sustainable and homogeneous source for a rapid and highly productive generation of phenotypically mature, functional MCs, and its principle allows for the investigation of disease- and patient-specific MC populations. Copyright © 2021 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.
| Authors | Luo Y, Fernandez Vallone V, He J, Frischbutter S, Kolkhir P, Moñino-Romero S, Stachelscheid H, Streu-Haddad V, Maurer M, Siebenhaar F, Scheffel J |
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| Journal | The Journal of allergy and clinical immunology |
| Publication Date | 2022 Mar;149(3):1060-1068.e4 |
| PubMed | 34371081 |
| DOI | 10.1016/j.jaci.2021.07.027 |