SNTA1-deficient human cardiomyocytes demonstrate hypertrophic phenotype and calcium handling disorder


SNTA1-deficient cardiomyocytes can be used to research the etiology, pathogenesis, and potential therapies for myocardial diseases. The SNTA1-deficient cardiomyocyte model suggests that the maintenance of cardiac calcium homeostasis is a key target in the treatment of myocardial-related diseases. © 2022. The Author(s).

Authors Dong T, Zhao Y, Jin HF, Shen L, Lin Y, Si LL, Chen L, Liu JC
Journal Stem cell research & therapy
Publication Date 2022 Jun 30;13(1):288
PubMed 35773684
PubMed Central PMC9248201
DOI 10.1186/s13287-022-02955-4

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