Human embryonic stem cell lines derived from single blastomeres of two 4-cell stage embryos
We report the successful derivation and characterization of two hESC lines from single blastomeres of four split 4-cell stage human embryos. These two hESC lines were derived from distinct embryos, proving that at least one of the 4-cell stage blastomeres is pluripotent.
|Authors||Geens M, Mateizel I, Sermon K, De Rycke M, Spits C, Cauffman G, Devroey P, Tournaye H, Liebaers I, Van de Velde H|
|Journal||Human reproduction (Oxford, England)|
|Publication Date||2009 Nov;24(11):2709-17|