Unlocking the secrets of NPSLE: the role of dendritic cell-secreted CCL2 in blood-brain barrier disruption
Summary
The secretion of CCL2 by dendritic cells induces pyroptosis in vascular endothelial cells, thereby promoting blood-brain barrier damage and triggering cognitive impairment in patients with systemic lupus erythematosus. Copyright © 2024 Wang, Zheng, Wang and Jia.
| Authors | Wang L, Zheng G, Wang P, Jia X |
|---|---|
| Journal | Frontiers in immunology |
| Publication Date | 2024;15:1343805 |
| PubMed | 39403387 |
| PubMed Central | PMC11472714 |
| DOI | 10.3389/fimmu.2024.1343805 |