Human cartilage model of the precocious osteoarthritis-inducingCOL2A1p.Arg719Cys reveals pathology-driving matrix defects and a failure of the ER proteostasis network to recognize the defective procollagen-II

Authors Yammine Kathryn M., Abularach Sophia Mirda, Xiong Michael, Kim Seo-yeon, Bikovtseva Agata A., Butty Vincent L., Schiavoni Richard P., Bateman John F., Lamandé Shireen R., Shoulders Matthew D.
Publication Date 2024-11-09
DOI 10.1101/2024.11.07.622468

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