MCRIi019-A

Registration Summary:

A P E C

1502

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	MCRIi019-A
Cite as:	MCRIi019-A (RRID:CVCL_A9XY)
Alternative name(s)	1502
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	7th September 2020
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Provider
Generator	Murdoch Children's Research Institute (MCRI)
External Databases
Cellosaurus	CVCL_A9XY
Wikidata	Q102114510
General Information
Publications	Kung LHW et al. CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A. Stem cell research. 2020 Oct;48:101962. Kung LHW et al. Generation of a miR-26b stem-loop knockout human iPSC line, MCRIi019-A-1, using CRISPR/Cas9 editing. Stem cell research. 2020 Dec 10;50:102118. Lilianty J et al. Generation of a heterozygous COL2A1 (p.G1113C) hypochondrogenesis mutation iPSC line, MCRIi019-A-7, using CRISPR/Cas9 gene editing. Stem cell research. 2021 Oct;56:102515. Humphreys PA et al. Developmental principles informing human pluripotent stem cell differentiation to cartilage and bone. Seminars in cell & developmental biology. 2022 Jul;127:17-36. Shabaldin Nikita A. et al. Molecular foundations of the etiology and pathogenesis of Legg-Calve-Perthes disease and prospects for targeted therapy: A literature review. Pediatric Traumatology, Orthopaedics and Reconstructive Surgery. 2022-09-22. Yammine KM et al. Using CRISPR/Cas9 to generate a heterozygous COL2A1 p.R719C iPSC line (MCRIi019-A-6) model of human precocious osteoarthritis. Stem cell research. 2023 Mar;67:103020. Li ZA et al. Synovial joint-on-a-chip for modeling arthritis: progress, pitfalls, and potential. Trends in biotechnology. 2023 Apr;41(4):511-527. Lamandé SR et al. Modeling human skeletal development using human pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 2023 May 9;120(19):e2211510120. Bombieri C et al. Advanced Cellular Models for Rare Disease Study: Exploring Neural, Muscle and Skeletal Organoids. International journal of molecular sciences. 2024 Jan 13;25(2).
* Is the cell line readily obtainable for third parties?	No
Subclones	MCRIi019-A-1 MCRIi019-A-2 MCRIi019-A-3 MCRIi019-A-4 MCRIi019-A-5 MCRIi019-A-6 MCRIi019-A-7

hIPSC Derivation

General