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MCRIi019-A
Registration Summary
:
A
P
E
C
1502
The cell line is
not submitted
yet.
(only basic data is shown)
General
Cell Line
hPSCreg name
MCRIi019-A
Cite as:
When citing this cell line, please use the hPSCreg name (see
Naming Tool
) and the corresponding Research Resource ID (RRID).
MCRIi019-A (RRID:CVCL_A9XY)
Alternative name(s)
1502
Cell line type
Human induced pluripotent stem cell (hiPSC)
Similar lines
No similar lines found.
Last update
7th September 2020
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Provider
Generator
Murdoch Children's Research Institute (MCRI)
External Databases
Cellosaurus
CVCL_A9XY
Wikidata
Q102114510
General Information
Publications
Kung LHW et al. CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A. Stem cell research. 2020 Oct;48:101962.
Kung LHW et al. Generation of a miR-26b stem-loop knockout human iPSC line, MCRIi019-A-1, using CRISPR/Cas9 editing. Stem cell research. 2020 Dec 10;50:102118.
Lilianty J et al. Generation of a heterozygous COL2A1 (p.G1113C) hypochondrogenesis mutation iPSC line, MCRIi019-A-7, using CRISPR/Cas9 gene editing. Stem cell research. 2021 Oct;56:102515.
Humphreys PA et al. Developmental principles informing human pluripotent stem cell differentiation to cartilage and bone. Seminars in cell & developmental biology. 2022 Jul;127:17-36.
Shabaldin Nikita A. et al. Molecular foundations of the etiology and pathogenesis of Legg-Calve-Perthes disease and prospects for targeted therapy: A literature review. Pediatric Traumatology, Orthopaedics and Reconstructive Surgery. 2022-09-22.
Yammine KM et al. Using CRISPR/Cas9 to generate a heterozygous COL2A1 p.R719C iPSC line (MCRIi019-A-6) model of human precocious osteoarthritis. Stem cell research. 2023 Mar;67:103020.
Li ZA et al. Synovial joint-on-a-chip for modeling arthritis: progress, pitfalls, and potential. Trends in biotechnology. 2023 Apr;41(4):511-527.
Lamandé SR et al. Modeling human skeletal development using human pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 2023 May 9;120(19):e2211510120.
Bombieri C et al. Advanced Cellular Models for Rare Disease Study: Exploring Neural, Muscle and Skeletal Organoids. International journal of molecular sciences. 2024 Jan 13;25(2).
Ali Eltahir Abdelrazig Mohamed et al. iPSCs chondrogenic differentiation for personalized regenerative medicine: a literature review. Stem Cell Research & Therapy. 2024-06-26.
Yammine KM et al. ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis. Life science alliance. 2024 Sep;7(9).
Yammine Kathryn M. et al. Human cartilage model of the precocious osteoarthritis-inducing
COL2A1
p.Arg719Cys reveals pathology-driving matrix defects and a failure of the ER proteostasis network to recognize the defective procollagen-II. . 2024-11-09.
* Is the cell line readily obtainable for third parties?
No
Subclones
MCRIi019-A-1
MCRIi019-A-2
MCRIi019-A-3
MCRIi019-A-4
MCRIi019-A-5
MCRIi019-A-6
MCRIi019-A-7
hIPSC Derivation
General
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