MCRIi019-A-7

Registration Summary:

A P E C

1502-COL2A1 p.G1113C

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	MCRIi019-A-7
Cite as:	MCRIi019-A-7 (RRID:CVCL_A1QP)
Alternative name(s)	1502-COL2A1 p.G1113C
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	30th August 2021
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Provider
Generator	Murdoch Children's Research Institute (MCRI)
External Databases
Cellosaurus	CVCL_A1QP
Wikidata	Q102114512
General Information
Publications	Lilianty J et al. Generation of a heterozygous COL2A1 (p.G1113C) hypochondrogenesis mutation iPSC line, MCRIi019-A-7, using CRISPR/Cas9 gene editing. Stem cell research. 2021 Oct;56:102515. Li ZA et al. Synovial joint-on-a-chip for modeling arthritis: progress, pitfalls, and potential. Trends in biotechnology. 2023 Apr;41(4):511-527. Lamandé SR et al. Modeling human skeletal development using human pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 2023 May 9;120(19):e2211510120. Bombieri C et al. Advanced Cellular Models for Rare Disease Study: Exploring Neural, Muscle and Skeletal Organoids. International journal of molecular sciences. 2024 Jan 13;25(2). Ali Eltahir Abdelrazig Mohamed et al. iPSCs chondrogenic differentiation for personalized regenerative medicine: a literature review. Stem Cell Research & Therapy. 2024-06-26. Yammine KM et al. ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis. Life science alliance. 2024 Sep;7(9).
Subclone of	MCRIi019-A

hIPSC Derivation

General
The source cell information can be found in the parental cell line MCRIi019-A.