Generation of induced pluripotent stem cell line (ZZUi011-A) from urine sample of a normal human


Urine cells collected from 200mL clean midsection urine of a 25-year-old healthy man were reprogrammed into pluripotent stem cells via Sendai virus delivery system. The induced pluripotent stem cells showed a normal karyotype and exhibited the potential to differentiate into three germ layers in a teratoma assay. This cell line may serve as a useful control for comparison with other pluripotent stem cell lines induced from somatic cells of patients with genetic neurodegenerative disorders. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Sun H, Zhang F, Wang Y, Wang Z, Zhang S, Xu Y, Shi C
Journal Stem cell research
Publication Date 2018 May;29:28-31
PubMed 29574173
DOI 10.1016/j.scr.2018.03.002

Research Projects

Cell Lines