SARS-CoV-2 pseudoparticles preferentially infect ectoderm in human embryonic tissues

Summary

Our findings provide strong evidence that cells in early post-implantation human embryos are susceptible to SARS-CoV-2 infection. The high level of infection in the ectodermal cells raises concern for potential teratogenic effects, particularly involving the nervous system. Future clinical studies should investigate neurological outcomes in infants born to mothers infected with SARS-CoV-2 during pregnancy. Copyright © 2026 Song and Talbot.

Authors Song A, Talbot P
Journal Frontiers in cell and developmental biology
Publication Date 2026;14:1733662
PubMed 42021929
PubMed Central PMC13095763
DOI 10.3389/fcell.2026.1733662

Research Projects

Cell Lines