AHQUi001-A-1

IPS35-2-R

General#

Cell Line

hPSCreg Name AHQUi001-A-1
Alternative name(s)
IPS35-2-R
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 14th October 2020
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Provider

Generator Affiliated Hospital of Qingdao University (AHQU)

External Databases

BioSamples SAMEA6516971

General Information

* Is the cell line readily obtainable for third parties?
No
Subclone of

Donor Information#

General Donor Information

Sex male
Ethnicity Chinese Han

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Familial hypertriglyceridemia (FHTG)
The donor is a carrier of a disease-associated mutation.
Genetic variants
LPL (target)
NM_000237.3:c.928 T>C
p.C310R
Heterozygous

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
No

External Databases (Donor)

BioSamples SAMEA6516985

Ethics#

Also have a look at the ethics information for the parental line AHQUi001-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation#

General

The source cell information can be found in the parental cell line AHQUi001-A.

Reprogramming method

Vector type Non-integrating
Vector Episomal
Genes
Is reprogramming vector detectable?
No
Methods used
PCR

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions#

Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzyme-free cell dissociation
EDTA
CO2 Concentration 5 %
Medium mTeSR™ 1

Characterisation#

No characterisation data could be found for this subclone. Please open parental cell line AHQUi001-A

Genotyping#

Karyotyping (Cell Line)

Other Genotyping (Cell Line)

Genetic Modification#

Disease/phenotype related modifications
hyperlipoproteinemia type IV
Familial hypertriglyceridemia (FHTG)
Synonyms
  • familial hypertriglyceridemia
  • VLDL hyperlipoproteinemia
  • Fredrickson type IV lipidaemia
  • Fredrickson type IV hyperlipoproteinemia
  • Endogenous hyperlipidaemia
  • Fredrickson type IV Lipidemia
show more synonyms
Genetic modifications
LPL (target)
Isogenic modification
NM_000237.3:c.928 T>C
p.C310R
Heterozygous
Repaired