AKOSi001-A

Registration Summary:

A P E C

NPC2 (p.E20X;C47F), GM18455-1 (NPC2), NPC2 (c.58G>C;c.140G>T)

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	AKOSi001-A
Cite as:	AKOSi001-A (RRID:CVCL_UL88)
Alternative name(s)	NPC2 (p.E20X;C47F), GM18455-1 (NPC2), NPC2 (c.58G>C;c.140G>T)
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	17th October 2019
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Provider
Generator	Translational Neurodegeneration Section "Albrecht Kossel" (AKOS)
External Databases
Cellosaurus	CVCL_UL88
Wikidata	Q93324065
General Information
Publications	Völkner C et al. Generation of the Niemann-Pick type C2 patient-derived iPSC line AKOSi001-A. Stem cell research. 2019 Dec;41:101606. Chulpanova Daria S. et al. iPSCs for modeling lysosomal storage diseases. Recent Advances in iPSC Disease Modeling, Volume 1. 2020-00-00. Pallottini V et al. Understanding and Treating Niemann-Pick Type C Disease: Models Matter. International journal of molecular sciences. 2020 Nov 26;21(23). Völkner C et al. Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Niemann-Pick Type C1. International journal of molecular sciences. 2021 Jan 12;22(2). Liedtke M et al. Pathophysiological In Vitro Profile of Neuronal Differentiated Cells Derived from Niemann-Pick Disease Type C2 Patient-Specific iPSCs Carrying the NPC2 Mutations c.58G>T/c.140G>T. International journal of molecular sciences. 2021 Apr 13;22(8).

hIPSC Derivation

General
Source cell line name	GM18455