AKOSi001-A

Registration Summary:

A P E C

NPC2 (p.E20X;C47F), GM18455-1 (NPC2), NPC2 (c.58G>C;c.140G>T)

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	AKOSi001-A
Cite as:	AKOSi001-A (RRID:CVCL_UL88)
Alternative name(s)	NPC2 (p.E20X;C47F), GM18455-1 (NPC2), NPC2 (c.58G>C;c.140G>T)
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	17th October 2019
User feedback	Written by on No feedback available yet. Login to share your feedback, experiences or results with the research community.
Provider
Generator	Translational Neurodegeneration Section "Albrecht Kossel" (AKOS)
External iPSC Databases
Cellosaurus	CVCL_UL88
Wikidata	Q93324065
General iPSC Information
Publications	Völkner C et al. Generation of the Niemann-Pick type C2 patient-derived iPSC line AKOSi001-A. Stem cell research. 2019 Dec;41:101606. Chulpanova Daria S. et al. iPSCs for modeling lysosomal storage diseases. Recent Advances in iPSC Disease Modeling, Volume 1. 2020-00-00. Pallottini V et al. Understanding and Treating Niemann-Pick Type C Disease: Models Matter. International journal of molecular sciences. 2020 Nov 26;21(23). Völkner C et al. Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Niemann-Pick Type C1. International journal of molecular sciences. 2021 Jan 12;22(2). Liedtke M et al. Pathophysiological In Vitro Profile of Neuronal Differentiated Cells Derived from Niemann-Pick Disease Type C2 Patient-Specific iPSCs Carrying the NPC2 Mutations c.58G>T/c.140G>T. International journal of molecular sciences. 2021 Apr 13;22(8).

iPSC Derivation

General
Source cell line name	GM18455