AKOSi004-A

Registration Summary:

A P E C

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	AKOSi004-A
Cite as:	AKOSi004-A (RRID:CVCL_A4DI)
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	18th April 2023
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Provider
Generator	Translational Neurodegeneration Section "Albrecht Kossel" (AKOS) Contact: Translational Neurodegeneration Section "Albrecht Kossel" (AKOS)
Owner	Translational Neurodegeneration Section "Albrecht Kossel" (AKOS)
External iPSC Databases
Cellosaurus	CVCL_A4DI
Wikidata	Q105506389
General iPSC Information
Publications	Völkner C et al. Generation of an iPSC line (AKOSi004-A) from fibroblasts of a female adult NPC1 patient, carrying the compound heterozygous mutation p.Val1023Serfs15/p.Gly992Arg and of an iPSC line (AKOSi005-A) from a female adult control individual. Stem cell research. 2020 Dec 15;50:102127. Völkner C et al. Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Niemann-Pick Type C1. International journal of molecular sciences. 2021 Jan 12;22(2). Völkner C et al. Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs15/p.G992R, Present the "Variant" Biochemical Phenotype of Niemann-Pick Type C1 Disease. International journal of molecular sciences. 2021 Nov 10;22(22). Gaudioso Á et al. Models to study basic and applied aspects of lysosomal storage disorders. Advanced drug delivery reviews. 2022 Nov;190:114532.
* Is the cell line readily obtainable for third parties?	No

iPSC Derivation

General