AKOSi006-A

A P E C

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iPSC Line
hPSCreg name	AKOSi006-A
Cite as:	AKOSi006-A (RRID:CVCL_A4DG)
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	21st October 2020
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Provider
Generator	Translational Neurodegeneration Section "Albrecht Kossel" (AKOS)
External iPSC Databases
Cellosaurus	CVCL_A4DG
Wikidata	Q105506395
General iPSC Information
Publications	Völkner C et al. Generation of an iPSC line (AKOSi006-A) from fibroblasts of an NPC1 patient, carrying the homozygous mutation p.I1061T (c.3182 T > C) and a control iPSC line (AKOSi007-A) using a non-integrating Sendai virus system. Stem cell research. 2020 Dec;49:102056. Völkner C et al. Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Niemann-Pick Type C1. International journal of molecular sciences. 2021 Jan 12;22(2). Efendic F et al. Generation of the human iPSC line AKOSi010-A from fibroblasts of a female FAHN patient, carrying the compound heterozygous mutation p.Gly45Arg/p.His319Arg. Stem cell research. 2022 Aug;63:102863. Glaß Hannes et al. Corrosion Products from Metallic Implants Induce ROS and Cell Death in Human Motoneurons In Vitro. Journal of Functional Biomaterials. 2023-07-25. Efendic F et al. Disrupted Myelination in FAHN: Insights from a Patient-Specific hiPSC Neuron-Oligodendrocyte Model. Cells. 2025 Aug 15;14(16).