CPGHi001-A

Registration Summary:

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General

iPSC Line
hPSCreg name	CPGHi001-A
Cite as:	CPGHi001-A (RRID:CVCL_A9XF)
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	7th September 2020
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Provider
Generator	Chinese PLA General Hospital (CPGH)
External iPSC Databases
Cellosaurus	CVCL_A9XF
Wikidata	Q102113715
General iPSC Information
Publications	Wang H et al. Generation of a human induced pluripotent stem cell line (CPGHi001-A) from a hearing loss patient with the TMC1 p.M418K mutation. Stem cell research. 2020 Dec;49:101982. Zhang Xiaolong et al. Progression of KCNQ4 related genetic hearing loss: a narrative review. Journal of Bio-X Research. 2021-12-30. Panda Naresh Kumar et al. Novel Cellular Stress Models with Implications in Understanding and Treating ENT Pathologies. Biomedical Translational Research. 2022-00-00. Wang R et al. Identification of a novel AIFM1 variant from a Chinese family with auditory neuropathy. Frontiers in genetics. 2022;13:1064823. Wang H et al. Generation of a gene corrected human isogenic iPSC line (CPGHi001-A-1) from a hearing loss patient with the TMC1 p.M418K mutation using CRISPR/Cas9. Stem cell research. 2022 Apr;60:102736. Nist-Lund C et al. Advancements in inner ear development, regeneration, and repair through otic organoids. Current opinion in genetics & development. 2022 Oct;76:101954. Durán-Alonso MB et al. Induced Pluripotent Stem Cells, a Stepping Stone to In Vitro Human Models of Hearing Loss. Cells. 2022 Oct 21;11(20). Luo Yi et al. Genetic correction of induced pluripotent stem cells from a DFNA36 patient results in morphologic and functional recovery of derived hair cell-like cells. Stem Cell Research & Therapy. 2024-01-02. Zhang Xiaolong et al. Natural History of KCNQ4p.G285S Related Hearing Loss, Construction of iPSC and Mouse Model. The Laryngoscope. 2024-05-00. Yin X et al. Exploiting urine-derived induced pluripotent stem cells for advancing precision medicine in cell therapy, disease modeling, and drug testing. Journal of biomedical science. 2024 May 9;31(1):47. Zueva AS et al. Isogenic induced pluripotent stem cell line ICGi036-A-1 from a patient with familial hypercholesterolaemia, derived by correcting a pathogenic variant of the gene LDLR c.530C>T. Vavilovskii zhurnal genetiki i selektsii. 2025 Apr;29(2):189-199. Francelin Carolina et al. Impact of Donor and Host Age on Systemic Cell Therapy to Treat Age-Related Macular Degeneration. Cells. 2025-09-01.
Subclones	CPGHi001-A-1

iPSC Derivation

General