CPGHi001-A-1

Cell Line

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External Databases

General Information

• Wang H et al. Generation of a gene corrected human isogenic iPSC line (CPGHi001-A-1) from a hearing loss patient with the TMC1 p.M418K mutation using CRISPR/Cas9. Stem cell research. 2022 Apr;60:102736.
• Nist-Lund C et al. Advancements in inner ear development, regeneration, and repair through otic organoids. Current opinion in genetics & development. 2022 Oct;76:101954.
• Durán-Alonso MB et al. Induced Pluripotent Stem Cells, a Stepping Stone to In Vitro Human Models of Hearing Loss. Cells. 2022 Oct 21;11(20).
• Luo Yi et al. Genetic correction of induced pluripotent stem cells from a DFNA36 patient results in morphologic and functional recovery of derived hair cell-like cells. Stem Cell Research & Therapy. 2024-01-02.
• Zhang Xiaolong et al. Natural History of KCNQ4p.G285S Related Hearing Loss, Construction of iPSC and Mouse Model. The Laryngoscope. 2024-05-00.
• Zueva AS et al. Isogenic induced pluripotent stem cell line ICGi036-A-1 from a patient with familial hypercholesterolaemia, derived by correcting a pathogenic variant of the gene LDLR c.530C>T. Vavilovskii zhurnal genetiki i selektsii. 2025 Apr;29(2):189-199.
• Francelin Carolina et al. Impact of Donor and Host Age on Systemic Cell Therapy to Treat Age-Related Macular Degeneration. Cells. 2025-09-01.

• CPGHi001-A

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