JMUi001-A-3

Registration Summary:

A P E C

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	JMUi001-A-3
Cite as:	JMUi001-A-3 (RRID:CVCL_A5QI)
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	17th December 2020
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Provider
Generator	Comprehensive Heart Failure Center, University Clinic Wuerzburg (UKWCHF)
External iPSC Databases
Cellosaurus	CVCL_A5QI
Wikidata	Q107115501
General iPSC Information
Publications	Janz A et al. CRISPR/Cas9-edited PKP2 knock-out (JMUi001-A-2) and DSG2 knock-out (JMUi001-A-3) iPSC lines as an isogenic human model system for arrhythmogenic cardiomyopathy (ACM). Stem cell research. 2021 May;53:102256. GÜLER KARA Hale et al. CRISPR-Cas Functional Genetic Screening: Traditional Review. Turkiye Klinikleri Journal of Medical Sciences. 2022-00-00. Walz K et al. Generation of a CRISPR/Cas9-edited Plakoglobin (JUP) knock-out (JMUi001-A-4) iPSC line to model the cardiac phenotype of arrhythmogenic cardiomyopathy. Stem cell research. 2023 Dec;73:103240. Gerritse Merel et al. Characteristics and pharmacological responsiveness in hiPSC models of inherited cardiomyopathy. Pharmacology & Therapeutics. 2025-08-00. Gramatiuk Svetlana M. et al. Development of an Arrhythmogenic Cardiomyopathy Model Using CRISPR-Cas9 and Homology-Directed Repair. Ukrainian Journal of Cardiovascular Surgery. 2025-09-25.
Subclone of	JMUi001-A

iPSC Derivation

General
The source cell information can be found in the parental cell line JMUi001-A.