LVIP04-NC-F2-1, Clone 5
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General
Cell Line |
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| hPSCreg name | LVPEIi001-C |
| Cite as: | LVPEIi001-C (RRID:CVCL_E4X8) |
| Alternative name(s) |
LVIP04-NC-F2-1, Clone 5
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| Cell line type | Human induced pluripotent stem cell (hiPSC) |
| Similar lines | No similar lines found. |
| Last update | 29th August 2025 |
| Notes | This is a clinical grade, healthy control, induced pluripotent stem cell (iPSC) line and was generated by the reprogramming of donor skin-derived human dermal fibroblasts (HDFs) using xeno-free reagents and integration-free CTS™ CytoTune™-iPS 2.1 Sendai Reprogramming Kit (Invitrogen, A34546, Lot No. 2LG140003) containing Sendai viral vectors encoding the human OCT4, SOX2, KLF4 and L-Myc genes. This iPSC line maintained proper colony morphology, expressed the stemness and pluripotency markers OCT4, SOX2, NANOG, KLF4, SSEA4, and exhibited a normal karyotype at passage 15. This line efficiently differentiates into all three lineages and could generate retinal organoids and mature retinal pigmented epithelial cells. |
| User feedback | |
Provider |
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| Generator | L.V. Prasad Eye Institute (LVPEI) |
External Databases |
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| Cellosaurus | CVCL_E4X8 |
General Information |
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| * Is the cell line readily obtainable for third parties? |
Yes Research use: allowed
Clinical use: allowed
Commercial use: allowed
Additional restrictions:
Terms and conditions apply for commercial use. The MATERIAL cannot be directly used in clinical trials. Any use of the cellular derivatives of the MATERIAL in academic clinical trials must comply with appropriate regional regulatory guidelines for Stem Cell Research and Pluripotent Stem Cell-Derived Cellular Therapies. The REQUESTOR must inform the ORIGINATOR about the intended use. The Limitted Use Label Licence (LULL) for the CTS™ CytoTune™ Technology apply and require prior information and approval from iPS Academia Japan, Inc. |
| Subclones | |
hIPSC Derivation
General |
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| Source cell line name | Human dermal fibroblast cells |
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