MCRIi001-A-4

Registration Summary:

A P E C

PB001-SOX9tdTOM-TRPV4pP799L, MCRIi001-A-2-TRPV4 p.P799L

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	MCRIi001-A-4
Cite as:	MCRIi001-A-4 (RRID:CVCL_A9Z4)
Alternative name(s)	PB001-SOX9tdTOM-TRPV4pP799L, MCRIi001-A-2-TRPV4 p.P799L
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	9th July 2020
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Provider
Generator	Murdoch Children's Research Institute (MCRI)
External iPSC Databases
Cellosaurus	CVCL_A9Z4
Wikidata	Q102114509
General iPSC Information
Publications	Nur Patria Y et al. CRISPR/Cas9 gene editing of a SOX9 reporter human iPSC line to produce two TRPV4 patient heterozygous missense mutant iPSC lines, MCRIi001-A-3 (TRPV4 p.F273L) and MCRIi001-A-4 (TRPV4 p.P799L). Stem cell research. 2020 Oct;48:101942. Humphreys PA et al. Developmental principles informing human pluripotent stem cell differentiation to cartilage and bone. Seminars in cell & developmental biology. 2022 Jul;127:17-36. Dicks AR et al. Chondrogenic Differentiation of Human-Induced Pluripotent Stem Cells. Methods in molecular biology (Clifton, N.J.). 2023;2598:87-114. Cotta GC et al. Reporter Alleles in hiPSCs: Visual Cues on Development and Disease. International journal of molecular sciences. 2024 Oct 13;25(20).
Subclone of	MCRIi001-A

iPSC Derivation

General
The source cell information can be found in the parental cell line MCRIi001-A.