SCHi001-A-1

AMN5-Corrected iPSC

The cell line is not validated yet.

General#

Cell Line

hPSCreg Name
SCHi001-A-1
Alternative name(s)
AMN5-Corrected iPSC
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 26th October 2021
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Provider

Generator Severance Children’s Hospital (SCH)

External Databases

BioSamples SAMEA10454450
CLO CLO_0103546

General Information

* Is the cell line readily obtainable for third parties?
No
Subclone of

Donor Information#

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Adrenoleukodystrophy
Synonyms
  • Adrenoleukodystrophy
  • Schilder Disease

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA10405029

Ethics#

Also have a look at the ethics information for the parental line SCHi001-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation#

General

The source cell information can be found in the parental cell line SCHi001-A.

Reprogramming method

Vector type Integrating
Vector Plasmid
Is the used vector excisable?
Unknown
Absence of reprogramming vector(s)?
Unknown
Reprogramming vectors silenced?

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions#

Medium mTeSR™ 1

Characterisation#

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR FACS Enzymatic Assay Expression Profiles
NANOG
Yes
SOX2
Yes
SSEA-4
Yes
POU5F1 (OCT-4)
Yes
TRA 1-60
Yes
TRA 1-81
Yes
Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
Morphology
Mesoderm
Ont Id: UBERON_0000926
Morphology
Ectoderm
Ont Id: UBERON_0000924
Morphology

Genotyping#

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
g-banding

Other Genotyping (Cell Line)

Genetic Modification#

Disease/phenotype related modifications
Adrenoleukodystrophy
Synonyms
  • Adrenoleukodystrophy
  • Schilder Disease
Genetic modifications
Isogenic modification
c.1534G>A
NM_000033.4
Mutated