SCHi001-A-1

AMN5-Corrected iPSC

General

Cell Line

hPSCreg Name
SCHi001-A-1
Alternative name(s)
AMN5-Corrected iPSC
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 26th October 2021
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Provider

Generator Severance Children’s Hospital (SCH)

External Databases

BioSamples SAMEA10454450
CLO CLO_0103546

General Information

* Is the cell line readily obtainable for third parties?
No
Subclone of

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Adrenoleukodystrophy
Synonyms
  • Adrenoleukodystrophy
  • Schilder Disease

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA10405029

Ethics

Also have a look at the ethics information for the parental line SCHi001-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

The source cell information can be found in the parental cell line SCHi001-A.

Reprogramming method

Vector type Integrating
Vector Plasmid
Is the used vector excisable?
Unknown
Absence of reprogramming vector(s)?
Unknown
Reprogramming vectors silenced?

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium mTeSR™ 1

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR FACS Enzymatic Assay Expression Profiles
NANOG
Yes
SOX2
Yes
SSEA-4
Yes
POU5F1 (OCT-4)
Yes
TRA 1-60
Yes
TRA 1-81
Yes
Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
Morphology
Mesoderm
Ont Id: UBERON_0000926
Morphology
Ectoderm
Ont Id: UBERON_0000924
Morphology

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
g-banding

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications
Adrenoleukodystrophy
Synonyms
  • Adrenoleukodystrophy
  • Schilder Disease
Genetic modifications
Isogenic modification
c.1534G>A
NM_000033.4
Mutated