UMi028-A

Registration Summary:

A P E C

ASE9203

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	UMi028-A
Cite as:	UMi028-A (RRID:CVCL_A1MH)
Alternative name(s)	ASE9203
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	3rd June 2020
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Provider
Generator	University of Miami - Miller School of Medicine (UM)
External iPSC Databases
Cellosaurus	CVCL_A1MH
Wikidata	Q102115077
General iPSC Information
Publications	Gosstola NC et al. Characterization of UMi028-A-1 stem cell line that contains a CRISPR/Cas9 induced hearing loss-associated variant (V60L (c.178G > T)) in the P2RX2 gene. Stem cell research. 2020 Dec;49:102017. Lu L et al. Application of CRISPR/Cas9 in Alzheimer's Disease. Frontiers in neuroscience. 2021;15:803894. Potjewyd FM et al. Exploration of Aberrant E3 Ligases Implicated in Alzheimer's Disease and Development of Chemical Tools to Modulate Their Function. Frontiers in cellular neuroscience. 2021;15:768655. Laverde-Paz MJ et al. Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene. Stem cell research. 2021 Apr;52:102258. Liu X et al. Generation and Genetic Correction of USH2A c.2299delG Mutation in Patient-Derived Induced Pluripotent Stem Cells. Genes. 2021 May 25;12(6). Sen T et al. CRISPR and iPSCs: Recent Developments and Future Perspectives in Neurodegenerative Disease Modelling, Research, and Therapeutics. Neurotoxicity research. 2022 Oct;40(5):1597-1623. Mollashahi B et al. Research and Therapeutic Approaches in Stem Cell Genome Editing by CRISPR Toolkit. Molecules (Basel, Switzerland). 2023 Feb 20;28(4). Wong Poh Kuan et al. The Promises and Pitfalls of CRISPR-Mediated Base Editing in Stem Cells. The CRISPR Journal. 2023-06-01. Cukier HN et al. An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons. Neurobiology of aging. 2023 Nov;131:182-195. Raffaele Ivana et al. CRISPR/Cas9 and iPSC-Based Therapeutic Approaches in Alzheimer’s Disease. Antioxidants. 2025-06-25.
Subclones	UMi028-A-1 UMi028-A-2

iPSC Derivation

General