YCMi001-B-1

Registration Summary:

A P E C

The cell line is not submitted yet.

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General

Cell Line
hPSCreg name	YCMi001-B-1
Cite as:	YCMi001-B-1 (RRID:CVCL_A9YY)
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	10th August 2020
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Provider
Generator	College of Medicine (YCM)
External Databases
Cellosaurus	CVCL_A9YY
Wikidata	Q102115140
General Information
Publications	Sung JJ et al. Generation of a gene edited hemophilia A patient-derived iPSC cell line, YCMi001-B-1, by targeted insertion of coagulation factor FVIII using CRISPR/Cas9. Stem cell research. 2020 Oct;48:101948. Ramamurthy RM et al. Comparison of different gene addition strategies to modify placental derived-mesenchymal stromal cells to produce FVIII. Frontiers in immunology. 2022;13:954984. Bhattacharjee G et al. Current approaches in CRISPR-Cas9 mediated gene editing for biomedical and therapeutic applications. Journal of controlled release : official journal of the Controlled Release Society. 2022 Mar;343:703-723. Jair Lara-Navarro I et al. Current Therapies in Hemophilia: From Plasma-Derived Factor Modalities to CRISPR/Cas Alternatives. The Tohoku journal of experimental medicine. 2022 Mar;256(3):197-207. De Pablo-Moreno Juan A. et al. Treatment of congenital coagulopathies, from biologic to biotechnological drugs: The relevance of gene editing (CRISPR/Cas). Thrombosis Research. 2023-11-00. Alayoubi Abdulfatah M. et al. CRISPR-Cas9 system: a novel and promising era of genotherapy for beta-hemoglobinopathies, hematological malignancy, and hemophilia. Annals of Hematology. 2024-06-00.
Subclone of	YCMi001-B

hIPSC Derivation

General
The source cell information can be found in the parental cell line YCMi001-B.