YCMi001-B-1

Registration Summary:

A P E C

The cell line is not submitted yet.

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General

Cell Line
hPSCreg Name	YCMi001-B-1
Cell line type	Human induced pluripotent stem cell (hiPSC)
Last update	10th August 2020
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Provider
Generator	College of Medicine (YCM)
External Databases
Cellosaurus	CVCL_A9YY
Wikidata	Q102115140
General Information
Publications	Sung JJ et al. Generation of a gene edited hemophilia A patient-derived iPSC cell line, YCMi001-B-1, by targeted insertion of coagulation factor FVIII using CRISPR/Cas9. Stem cell research. 2020 Oct;48:101948. Ramamurthy RM et al. Comparison of different gene addition strategies to modify placental derived-mesenchymal stromal cells to produce FVIII. Frontiers in immunology. 2022;13:954984. Bhattacharjee G et al. Current approaches in CRISPR-Cas9 mediated gene editing for biomedical and therapeutic applications. Journal of controlled release : official journal of the Controlled Release Society. 2022 Mar;343:703-723. Jair Lara-Navarro I et al. Current Therapies in Hemophilia: From Plasma-Derived Factor Modalities to CRISPR/Cas Alternatives. The Tohoku journal of experimental medicine. 2022 Mar;256(3):197-207.
Subclone of	YCMi001-B

hIPSC Derivation

General
The source cell information can be found in the parental cell line YCMi001-B.