General

iPSC Line
hPSCreg name	BCHi032-A-1
Cite as: When citing this cell line, please use the hPSCreg name (see Naming Tool ) and the corresponding Research Resource ID (RRID).	BCHi032-A-1
Alternative name(s)	HNDS0038-01#A Pass-Match-Control
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	BCHi032-A-2 (HNDS0038-01#A CC19(+/+)) Donor diseases: FOXG1 syndrome BCHi032-A-3 (HNDS0038-01#A CC29(+/+)) Donor diseases: FOXG1 syndrome BCHi032-A (HNDS0038-01#A) Donor diseases: FOXG1 syndrome BCHi034-A-1 (HNDS0181-01#F CNC27(+/-)) Donor diseases: FOXG1 syndrome BCHi034-A-2 (HNDS0181-01#F CNC33(+/-)) Donor diseases: FOXG1 syndrome BCHi034-A-3 (HNDS0181-01#F CC2(+/+)) Donor diseases: FOXG1 syndrome BCHi034-A-4 (HNDS0181-01#F CC7(+/+)) Donor diseases: FOXG1 syndrome BCHi031-A-1 (HNDS0032-01#A CNC6(+/-)) Donor diseases: FOXG1 syndrome BCHi031-A-2 (HNDS0032-01#A CNC20(+/-)) Donor diseases: FOXG1 syndrome BCHi031-A-3 (HNDS0032-01#A CC10(+/+)) Donor diseases: FOXG1 syndrome BCHi031-A-4 (HNDS0032-01#A CC31(+/+)) Donor diseases: FOXG1 syndrome BCHi033-A-1 (HNDS0060-01#B CNC18(+/-)) Donor diseases: FOXG1 syndrome BCHi033-A-2 (HNDS0060-01#B CNC22(+/-)) Donor diseases: FOXG1 syndrome BCHi033-A-3 (HNDS0060-01#B CC9(+/+)) Donor diseases: FOXG1 syndrome BCHi033-A-4 (HNDS0060-01#B CC21(+/+)) Donor diseases: FOXG1 syndrome BCHi028-A-1 (HNDS0171-01#A CNC2(+/-)) Donor diseases: FOXG1 syndrome BCHi028-A-2 (HNDS0171-01#A CC10(+/+)) Donor diseases: FOXG1 syndrome BCHi028-A-3 (HNDS0171-01#A CNC12(+/-)) Donor diseases: FOXG1 syndrome BCHi028-A-4 (HNDS0171-01#A CC16(+/+)) Donor diseases: FOXG1 syndrome BCHi034-A (HNDS0181-01#F) Donor diseases: FOXG1 syndrome BCHi033-A (HNDS0060-01#B) Donor diseases: FOXG1 syndrome BCHi028-A (HNDS0171-01#A) Donor diseases: FOXG1 syndrome BCHi031-A (HNDS0032-01#A) Donor diseases: FOXG1 syndrome
Last update	31st May 2024
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Provider
Generator	Children's Hospital (BCH)
External iPSC Databases
BioSamples	SAMEA115578028
General iPSC Information
* Is the cell line readily obtainable for third parties?	Yes Research use: allowed Clinical use: not allowed Commercial use: not allowed
Subclone of	BCHi032-A

iPSC Genetic Modification

Disease/phenotype related modifications

FOXG1 syndrome Synonyms FOXG1-related epileptic-dyskinetic encephalopathy Genetic modifications FOXG1 (target) Type of iPSC Modification Variant Chromosome location Cytoband location: 14q12 Nucleotide sequence variant in HGVS format NM_005249.5: c.653A>G; p.Y218C Is the modification homozygous or heterozygous? Heterozygous

Donor Information

General Donor Information
Sex	female
Ethnicity	White
Phenotype and Disease related information (Donor)
Diseases	A disease was diagnosed. FOXG1 syndrome The donor is affected. Synonyms FOXG1-related epileptic-dyskinetic encephalopathy
External Databases (Donor)
BioSamples	SAMEA115527673

Ethics

Also have a look at the ethics information for the parental line BCHi032-A .

Is there an MTA available for the cell line?	No
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

iPSC Derivation

General
The source cell information can be found in the parental cell line BCHi032-A.
Reprogramming method
Vector type	Non-integrating
Vector	Sendai virus
Vector free reprogramming
Other
Derived under xeno-free conditions	Unknown
Derived under GMP?	Unknown
Available as clinical grade?	Unknown

iPSC Culture Conditions

Surface coating	Matrigel/Geltrex
Feeder cells	No
Medium	Other medium: Base medium: Stemflex Main protein source: Bovine Serum Albumine (BSA) Serum concentration: 1 %
Has Rock inhibitor (Y27632) been used at passage previously with this iPSC line?	Yes
Has Rock inhibitor (Y27632) been used at cryo previously with this iPSC line?	No
Has Rock inhibitor (Y27632) been used at thaw previously with this iPSC line?	Yes

iPSC Characterisation

No characterisation data could be found for this subclone. Please open parental cell line BCHi032-A .

Genotyping

Karyotyping (iPSC Line)
Has the iPSC line karyotype been analysed?	Yes 46, XX; no clonal abnormalities Karyotyping method: G-Banding
Other Genotyping (iPSC Line)