BIONi010-C-37

Registration Summary:

A P E C

APP V717I (London mutation)

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	BIONi010-C-37
Cite as:	BIONi010-C-37 (RRID:CVCL_UR26)
Alternative name(s)	APP V717I (London mutation)
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	7th March 2023
User feedback	Written by on No feedback available yet. Login to share your feedback, experiences or results with the research community.
Provider
Generator	Bioneer (BION)
External iPSC Databases
Cellosaurus	CVCL_UR26
Wikidata	Q93426793
General iPSC Information
Publications	Frederiksen HR et al. Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene. Stem cell research. 2019 Jan;34:101368. Ameen AO et al. Metabolic Astrocytic Support with Decanoic Acid Enhances Energy Metabolism in Alzheimer's Disease Models. Cells. 2025 Dec 16;14(24).
* Is the cell line readily obtainable for third parties?	Yes Research use: allowed Clinical use: not allowed Commercial use: not allowed
Subclone of	BIONi010-C

iPSC Derivation

General
The source cell information can be found in the parental cell line BIONi010-C.