HVRDi001-A-1

Registration Summary:

A P E C

TYP1fADb

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	HVRDi001-A-1
Cite as:	HVRDi001-A-1 (RRID:CVCL_JV24)
Alternative name(s)	TYP1fADb
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	24th August 2017
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Provider
Generator	Harvard University (HVRD) Contact: Brigham and Women's Hospital (BWH)
Owner	Brigham and Women's Hospital (BWH)
Distributors	WiCell Research Institute - National Stem Cell Bank
External Databases
Cellosaurus	CVCL_JV24
Wikidata	Q54896947
General Information
Publications	Muratore CR et al. The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons. Human molecular genetics. 2014 Jul 1;23(13):3523-36. Fang J et al. Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease. Nature aging. 2021 Dec;1(12):1175-1188. Fang J et al. Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer’s disease. Nat Aging. 2021-12-01. James E et al. Human iPSC-derived retinal organoids develop robust Alzheimer's disease neuropathology. Frontiers in cellular neuroscience. 2024;18:1340448.
Subclone of	HVRDi001-A

hIPSC Derivation

General
The source cell information can be found in the parental cell line HVRDi001-A.