HVRDi015-A

Registration Summary:

A P E C

SMA 3-9C Sev

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	HVRDi015-A
Cite as:	HVRDi015-A (RRID:CVCL_WS08)
Alternative name(s)	SMA 3-9C Sev
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	2nd March 2021
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Provider
Generator	Harvard University (HVRD)
External iPSC Databases
Cellosaurus	CVCL_WS08
BioSamples	SAMEA8325235
Wikidata	Q94310003
General iPSC Information
Publications	Rodriguez-Muela N et al. Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease. Cell reports. 2017 Feb 7;18(6):1484-1498. Rodriguez-Muela N et al. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes. The Journal of clinical investigation. 2018 Jul 2;128(7):3008-3023. Grass T et al. Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation. Cell reports. Medicine. 2024 Aug 20;5(8):101659. Rosignol Ines et al. Altered lysosomal biology impairs motor neuron survival via TFEB dysregulation in spinal muscular atrophy. . 2025-07-10.
* Is the cell line readily obtainable for third parties?	No

iPSC Derivation

General