HVRDi016-A

Registration Summary:

A P E C

PNN 1-38 (SMA)

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	HVRDi016-A
Cite as:	HVRDi016-A (RRID:CVCL_WS09)
Alternative name(s)	PNN 1-38 (SMA)
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	27th January 2022
User feedback	Written by on No feedback available yet. Login to share your feedback, experiences or results with the research community.
Provider
Generator	Harvard University (HVRD)
External Databases
Cellosaurus	CVCL_WS09
Wikidata	Q94310009
BioSamples	SAMEA12598003
General Information
Publications	Ng SY et al. Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy. Cell stem cell. 2015 Nov 5;17(5):569-84. Rodriguez-Muela N et al. Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease. Cell reports. 2017 Feb 7;18(6):1484-1498. Rodriguez-Muela N et al. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes. The Journal of clinical investigation. 2018 Jul 2;128(7):3008-3023. Grass T et al. Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation. Cell reports. Medicine. 2024 Aug 20;5(8):101659.
* Is the cell line readily obtainable for third parties?	No

hIPSC Derivation

General