HVRDi017-A

Registration Summary:

A P E C

SMA 1-51 (type II)

The cell line is not submitted yet.

(only basic data is shown)

General

Cell Line
hPSCreg name	HVRDi017-A
Cite as:	HVRDi017-A (RRID:CVCL_WS10)
Alternative name(s)	SMA 1-51 (type II)
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	22nd May 2019
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Provider
Generator	Harvard University (HVRD)
External Databases
BioSamples	SAMEA5746312
Cellosaurus	CVCL_WS10
Wikidata	Q94310013
General Information
Publications	Ng SY et al. Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy. Cell stem cell. 2015 Nov 5;17(5):569-84. Rodriguez-Muela N et al. Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease. Cell reports. 2017 Feb 7;18(6):1484-1498. Rodriguez-Muela N et al. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes. The Journal of clinical investigation. 2018 Jul 2;128(7):3008-3023. Grass T et al. Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation. Cell reports. Medicine. 2024 Aug 20;5(8):101659.
* Is the cell line readily obtainable for third parties?	No

hIPSC Derivation

General
Source cell line name	HVRDi017-A