IITi001-A

Cell Line

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External Databases

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• Schick R et al. Functional abnormalities in induced Pluripotent Stem Cell-derived cardiomyocytes generated from titin-mutated patients with dilated cardiomyopathy. PloS one. 2018;13(10):e0205719.
• Eisen B et al. Generation of Duchenne muscular dystrophy patient-specific induced pluripotent stem cell line lacking exons 45-50 of the dystrophin gene (IITi001-A). Stem cell research. 2018 May;29:111-114.
• D'Amario D et al. Dystrophin Cardiomyopathies: Clinical Management, Molecular Pathogenesis and Evolution towards Precision Medicine. Journal of clinical medicine. 2018 Sep 19;7(9).
• Echigoya Y et al. Multiple Exon Skipping in the Duchenne Muscular Dystrophy Hot Spots: Prospects and Challenges. Journal of personalized medicine. 2018 Dec 7;8(4).
• Piga D et al. Human induced pluripotent stem cell models for the study and treatment of Duchenne and Becker muscular dystrophies. Therapeutic advances in neurological disorders. 2019;12:1756286419833478.
• Eisen B et al. Electrophysiological abnormalities in induced pluripotent stem cell-derived cardiomyocytes generated from Duchenne muscular dystrophy patients. Journal of cellular and molecular medicine. 2019 Mar;23(3):2125-2135.
• Casamassa A et al. A Link between Genetic Disorders and Cellular Impairment, Using Human Induced Pluripotent Stem Cells to Reveal the Functional Consequences of Copy Number Variations in the Central Nervous System-A Close Look at Chromosome 15. International journal of molecular sciences. 2020 Mar 9;21(5).
• Rovina D et al. "Betwixt Mine Eye and Heart a League Is Took": The Progress of Induced Pluripotent Stem-Cell-Based Models of Dystrophin-Associated Cardiomyopathy. International journal of molecular sciences. 2020 Sep 23;21(19).
• Jimenez-Vazquez EN et al. SNTA1 gene rescues ion channel function and is antiarrhythmic in cardiomyocytes derived from induced pluripotent stem cells from muscular dystrophy patients. eLife. 2022 Jun 28;11.
• Willi L et al. Bioenergetic and Metabolic Impairments in Induced Pluripotent Stem Cell-Derived Cardiomyocytes Generated from Duchenne Muscular Dystrophy Patients. International journal of molecular sciences. 2022 Aug 29;23(17).
• Eisen Binyamin et al. Modeling Duchenne Muscular Dystrophy Cardiomyopathy with Patients’ Induced Pluripotent Stem-Cell-Derived Cardiomyocytes. International Journal of Molecular Sciences. 2023-05-12.

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