INSRMi015-A

General

Cell Line

hPSCreg name INSRMi015-A
Cite as:
INSRMi015-A (RRID:CVCL_C9DU)
Cell line type Human induced pluripotent stem cell (hiPSC)
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Last update 31st August 2023
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Provider

Generator INSERM (INSRM)
Contact:
INSERM (INSRM)

External Databases

BioSamples SAMEA114268634
Cellosaurus CVCL_C9DU
Wikidata Q123032714

General Information

Publications
* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: allowed
Commercial use: not allowed

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
LQT2 syndrome
The donor is a carrier of a disease-associated mutation and affected.
Synonyms
  • Ventricular arrhythmia associated with long QT syndrome
  • Long QT Syndrome
  • LONG QT SYNDROME

External Databases (Donor)

BioSamples SAMEA114267093

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? No
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? No
Please provide contact information of the holder of the original Donor Information Sheet. Prof. Jean-Luc Pasquié; jl-pasquie@chu-montpellier.fr
Do you (Depositor/Provider) hold the original Donor Consent Form? Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? Yes
How may genetic information associated with the cell line be accessed? Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? CHU of Montpellier
Approval number CPP 1003-HPS2
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell type
A sample of peripheral blood mononuclear cells.
Synonyms
  • Peripheral Blood Mononuclear Cell Specimen
  • PBMC Specimen
  • PBMC Sample
  • Peripheral Blood Mononuclear Cell Sample
  • Peripheral Blood Mononuclear Cell (PBMC)
show more synonyms

Reprogramming method

Vector type Non-integrating
Vector Sendai virus
Genes
Is reprogramming vector detectable?
Unknown
Methods used
Immunostaining, PCR, RT-PCR, Sequencing
Files and images showing reprogramming vector expressed or silenced

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium Essential 8™

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
TRA 1-60
Yes
SSEA-4
Yes
Morphology pictures
Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
In vivo teratoma
Epithelium
Ont Id: NCIT_C12710
Cartilage Element
Ont Id: UBERON_0007844
In vivo teratoma
Smooth Muscle Cell
Ont Id: CL_0000192
In vivo teratoma
Ectoderm
Ont Id: UBERON_0000924
In vivo teratoma
Neural Tube
Ont Id: NCIT_C34226

Microbiology / Virus Screening

Mycoplasma Negative

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Unknown

Other Genotyping (Cell Line)