MRIi003-A-11

AAVS-CAG-DTPA-R homozygous

General

Cell Line

hPSCreg name MRIi003-A-11
Cite as:
MRIi003-A-11
Alternative name(s)
AAVS-CAG-DTPA-R homozygous
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines No similar lines found.
Last update 6th August 2024
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Provider

Generator Klinikum rechts der Isar (MRI)

External Databases

BioSamples SAMEA115906080

General Information

* Is the cell line readily obtainable for third parties?
No
Subclone of

Donor Information

General Donor Information

Sex male
Ethnicity Caucasian

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
No

External Databases (Donor)

BioSamples SAMEA8976597

Ethics

Also have a look at the ethics information for the parental line MRIi003-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

The source cell information can be found in the parental cell line MRIi003-A.

Reprogramming method

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Characterisation

No characterisation data could be found for this subclone. Please open parental cell line MRIi003-A .

Genotyping

Karyotyping (Cell Line)

Other Genotyping (Cell Line)

Genetic Modification

Genetic modifications not related to a disease
PPP1R12C (target)
Gene knock-in
19q13; 19q13-qter
inserted transgene: the membrane-anchored Anticalin protein receptor (DTPA-R) driven by the CAG promoter; DTPA-R is used as novel reporter gene system for PET imaging
CRISPR-associated (CRISPR/Cas) System