SCSe001-A-3

iPSC Line

Provider

External iPSC Databases

General iPSC Information

• Leavens KF et al. Generation of a double insulin and somatostatin reporter line, SCSe001-A-3, for the advancement of stem cell-derived pancreatic islets. Stem cell research. 2021 Jan;50:102112.
• Halliez C et al. In vitro beta-cell killing models using immune cells and human pluripotent stem cell-derived islets: Challenges and opportunities. Frontiers in endocrinology. 2022;13:1076683.
• Leavens KF et al. Stem cell-based multi-tissue platforms to model human autoimmune diabetes. Molecular metabolism. 2022 Dec;66:101610.
• Wilken MB et al. Generation of a human Tropomyosin 1 knockout iPSC line. Stem cell research. 2023 Sep;71:103161.
• Takasaki K et al. Generation of CHOPi-008-B, a euploid iPSC line from a patient with Trisomy 21 and a GATA1 mutation. Stem cell research. 2023 Oct;72:103198.
• Pollock Samuel D. et al. Scalable generation of 3D pancreatic islet organoids from human pluripotent stem cells in suspension bioreactors. STAR Protocols. 2023-12-00.
• Wang Chencheng et al. Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling. Frontiers in Bioengineering and Biotechnology. 2024-06-12.
• Zanfrini Elisa et al. Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters. Scientific Reports. 2024-08-27.
• Mar Samantha et al. Tracking Insulin- and Glucagon-Expressing Cells In Vitro and In Vivo Using a Double-Reporter Human Embryonic Stem Cell Line. Diabetes. 2025-02-01.

• SCSe001-A