General

Cell Line

hPSCreg name SDPHi002-A
Cite as:
SDPHi002-A (RRID:CVCL_C6SM)
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
CRICKi022-A
(iFCI031)
Donor diseases:
lung cancer
CRICKi016-A
(iFCI021 Clone 7)
Donor diseases:
lung cancer
CRICKi017-A
(iFCI022 Clone 4)
Donor diseases:
lung cancer
Last update 17th April 2023
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Provider

Generator Shandong Provincial Hospital Affiliated to Shandong First Medical University (SDPH)

External Databases

BioSamples SAMEA112763047
Cellosaurus CVCL_C6SM
Wikidata Q117704861

General Information

Publications
* Is the cell line readily obtainable for third parties?
No

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Synonyms
  • adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation
  • adenocarcinoma of lung, somatic
  • cancer of lung
  • lung cancer
  • lung cancer, protection against, autosomal dominant, somatic mutation
  • lung cancer, resistance to, autosomal dominant, somatic mutation
  • lung cancer, somatic
  • lung cancer, susceptibility to, autosomal dominant, somatic mutation
  • malignant lung neoplasm
  • malignant lung tumor
  • malignant lung tumour
  • malignant neoplasm of lung
  • malignant neoplasm of the lung
  • malignant tumor of lung
  • malignant tumor of the lung
  • malignant tumour of lung
  • malignant tumour of the lung
  • nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation
  • nonsmall cell lung cancer, somatic
  • nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation
  • Nonsmall cell lung cancer
  • alveolar cell carcinoma
  • lung cancer, protection against
  • lung neoplasm
show more synonyms

External Databases (Donor)

BioSamples SAMEA112763048

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? No
Provide contact information of the holder of the original Donor Information Sheet: Professor Yi Liu, Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Jinan, China, y_liu99@sina.com
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? Yes
Contact information / weblink Professor Yi Liu, Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Jinan, China, y_liu99@sina.com
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed? No information
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? Shandong Provincial Hospital Affiliated to Shandong First Medical University
Approval number SWYX: NO. 2022-293
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell line name PBMC
Source cell type
A peripheral blood cell with a single nucleus. This category includes lymphocytes and monocytes.
Synonyms
  • PERIPHERAL BLOOD MONONUCLEAR CELL
  • Peripheral Blood Mononuclear Cell
  • PBMC
Source cell origin
A liquid tissue; its major function is to transport oxygen throughout the body. It also supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection. Several hormones also travel in the blood.
Synonyms
  • Reticuloendothelial System, Blood
  • Peripheral Blood
  • peripheral blood
  • blood
  • Blood
  • Whole Blood
  • BLOOD
  • portion of blood
  • vertebrate blood
show more synonyms
Source cell type (free text) Arm Venipuncture

Reprogramming method

Vector type Non-integrating
Vector Episomal

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium mTeSR™ 1

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
In vitro spontaneous differentiation
Mesoderm
Ont Id: UBERON_0000926
In vitro spontaneous differentiation
Ectoderm
Ont Id: UBERON_0000924
In vitro spontaneous differentiation

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46, XY

Other Genotyping (Cell Line)