General

Cell Line
hPSCreg name	UKWMPi016-A
Cite as: When citing this cell line, please use the hPSCreg name (see Naming Tool ) and the corresponding Research Resource ID (RRID).	UKWMPi016-A
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	UKWi008-A (PARK2-9 CL12) Donor diseases: attention deficit-hyperactivity disorder TMPi014-A (MR030 c1, MR-030 c1) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi014-B (MR030 c2, MR-030 c2) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi015-A (NR-002 c2, NR002 c2) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi015-B (NR002 c21, NR-002 c21) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi016-A (NR003 c6, NR-003 c6) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi016-B (NR003 c9, NR-003 c9) Donor diseases: Attention Deficit Hyperactivity Disorder MICCNi002-A (ADHD Stem Cell Study_subject 5, clone A1, hiPSC_03 affected sibling) Donor diseases: attention deficit hyperactivity disorder MICCNi002-B (ADHD Stem Cell Study_subject 5, hiPSC_03 affected sibling, clone A16) Donor diseases: attention deficit hyperactivity disorder TMPi008-B (MR-013 c13, MR013 c13) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi006-A (MR-001 x3, MR001 x3, MR-001 c3, MR001 c3) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi006-B (MR001 x15, MR-001 x15, MR-001 c15, MR001 c15) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi007-A (MR-010 c3, MR010 c3) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi007-B (MR-010 c18, MR010 c18) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi012-A (MR-023 c17, MR023 c17) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi008-A (MR-013 c3, MR013 c3) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi012-B (MR023 c22, MR-023 c22) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi009-A (MR014 c12.1.1, MR-014 c12, MR-014 c12.1.1, MR014 c12) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi009-B (MR014 c27, MR-014 c27) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi013-A (MR-012, MR012) Donor diseases: Attention Deficit Hyperactivity Disorder TMPi013-B (MR-012 c12, MR012 c12) Donor diseases: Attention Deficit Hyperactivity Disorder UKWi008-A-1 (PARK2-9 CL22) Donor diseases: attention deficit-hyperactivity disorder
Last update	11th February 2026
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Provider
Generator	Division of Molecular Psychiatry, Center of Mental Health (UKWMP) Contact: Division of Molecular Psychiatry, Center of Mental Health (UKWMP)
External Databases
BioSamples	SAMEA121347074
General Information
* Is the cell line readily obtainable for third parties?	Yes Research use: allowed Clinical use: not allowed Commercial use: not allowed

Donor Information

General Donor Information
Sex	female
Phenotype and Disease related information (Donor)
Diseases	A disease was diagnosed. Attention deficit-hyperactivity disorder Synonyms attention deficit hyperactivity disorder attention deficit-hyperactivity disorder attention deficit/hyperactivity disorder ADHD show more synonyms show less synonyms
External Databases (Donor)
BioSamples	SAMEA121347075

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived?	Yes
Was the consent voluntarily given?	Yes
Has the donor been informed that participation will not directly influence their personal treatment?	Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor?	Yes
Do you (Depositor/Provider) hold the original Donor Consent Form?	Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised.	pseudonymised
Does consent explicitly allow the derivation of pluripotent stem cells?	Yes
* Does consent expressly prevent the derivation of pluripotent stem cells?	No
* Does consent pertain to a specific research project?	Yes
Details on restriction to research project	see Patient information sheet
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world?	No
How may genetic information associated with the cell line be accessed?	Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample?	No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions?	Yes
Name of accrediting authority involved?	Ethics committee University of Würzburg
Approval number	Ethical approval number 188/19-me
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General
Source cell type	Fibroblasts
Reprogramming method
Vector type	Non-integrating
Vector	Sendai virus
Is reprogramming vector detectable?	No
Methods used	PCR
Vector free reprogramming
Other
Derived under xeno-free conditions	Unknown
Derived under GMP?	Unknown
Available as clinical grade?	Unknown

Culture Conditions

Medium

Other medium: Base medium: StemMACS™ iPS-Brew XF medium Main protein source: Serum concentration: %

Characterisation

Analysis of Undifferentiated Cells

Marker Expression

Marker	Expressed	Immunostaining	RT-PCR	Flow Cytometry	Enzymatic Assay	Expression Profiles
POU5F1 (OCT-4)	Yes
SSEA-4	Yes
TRA 1-60	Yes

Differentiation Potency

Endoderm

Endoderm
Ont Id: UBERON_0000925

In vitro directed differentiation

Mesoderm

Mesoderm
Ont Id: UBERON_0000926

In vitro directed differentiation

Ectoderm

Ectoderm
Ont Id: UBERON_0000924

In vitro directed differentiation

Genotyping

Karyotyping (Cell Line)
Has the cell line karyotype been analysed?	Unknown
Other Genotyping (Cell Line)