MICCNi002-A

ADHD Stem Cell Study_subject 5, clone A1, hiPSC_03 affected sibling

General

Cell Line

hPSCreg name MICCNi002-A
Cite as:
MICCNi002-A (RRID:CVCL_UM15)
Alternative name(s)
ADHD Stem Cell Study_subject 5, clone A1, hiPSC_03 affected sibling
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
MICCNi002-B
(ADHD Stem Cell Study_subject 5, hiPSC_03 affected sibling, clone A16)
Donor diseases:
attention deficit hyperactivity disorder
TMPi008-B
(MR-013 c13, MR013 c13)
Donor diseases:
Attention Deficit Hyperactivity Disorder
TMPi012-A
(MR-023 c17, MR023 c17)
Donor diseases:
Attention Deficit Hyperactivity Disorder
TMPi012-B
(MR023 c22, MR-023 c22)
Donor diseases:
Attention Deficit Hyperactivity Disorder
Last update 26th January 2021
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Provider

Generator ​Monash Institute of Cognitive and Clinical Neurosciences (MICCN)

External Databases

Cellosaurus CVCL_UM15
BioSamples SAMEA8093239
Wikidata Q95989695

General Information

Publications
* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed

Donor Information

General Donor Information

Sex male
Ethnicity Caucasian

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Synonyms
  • ADHD
  • Syndromes, Hyperkinetic
  • Attention Deficit Hyperactivity Disorders
  • Attention Deficit Disorder with Hyperactivity
  • ATTENTION DEFICIT HYPERACTIVITY DIS
  • Brain Dysfunction, Minimal
  • Minimal Brain Dysfunction
  • Deficit Disorders, Attention
  • Attention Deficit Disorders with Hyperactivity
  • Deficit Disorder, Attention
  • ATTENTION DEFICIT DIS
  • Hyperkinetic Syndrome
  • Attention Deficit Disorders
  • Disorder, Attention Deficit
  • Disorders, Attention Deficit
  • ADDH
  • ATTENTION DEFICIT DIS WITH HYPERACTIVITY
  • Dysfunction, Minimal Brain
  • attention deficit-hyperactivity disorder
  • attention deficit/hyperactivity disorder
  • attention deficit hyperactivity disorder
  • Attention Deficit Disorder
show more synonyms

Karyotyping (Donor)

Has the donor karyotype been analysed?
Yes
46,XY
Karyotyping method: G-Banding

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA4984142

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? Yes
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? No
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. pseudonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent expressly prevent the derivation of pluripotent stem cells? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? Yes
How may genetic information associated with the cell line be accessed? Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? Monash University Human Research Ethics Committee
Approval number CF15/2566 - 2015001048
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the PROPOSED PROJECT, involving use of donated embryo/tissue or derived cells? No
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell type
A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood.
Source cell origin
A fluid that is composed of blood plasma and erythrocytes.
Synonyms
  • portion of blood
  • vertebrate blood
  • whole blood

Reprogramming method

Vector type Non-integrating
Vector Sendai virus
Genes
Is reprogramming vector detectable?
No
Methods used
RT-PCR

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium Essential 8™

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
TRA 1-60
Yes
NANOG
Yes
Klf4
Yes
POU5F1 (OCT-4)
Yes
Self-renewal
Unknown
Endoderm
Unknown
Mesoderm
Unknown
Ectoderm score
Positive

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46,XY
Karyotyping method: G-Banding

Other Genotyping (Cell Line)