UMGi014-A

Cell Line

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• Cyganek L et al. Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes. JCI insight. 2018 Jun 21;3(12).
• El-Battrawy I et al. Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Frontiers in cell and developmental biology. 2019;7:261.
• Khadjeh S et al. CRISPLD1: a novel conserved target in the transition to human heart failure. Basic research in cardiology. 2020 Mar 7;115(3):27.
• Huang M et al. Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy. Frontiers in cardiovascular medicine. 2021;8:777463.
• Sattler K et al. TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes. Scientific reports. 2021 Jul 19;11(1):14689.
• Li Wener et al. Effects of Hydroxychloroquine and Azithromycin on iPSC-derived Cardiomyocytes: Considerations for the Treatment of COVID-19 Patients. . 2021-08-19.
• Barbarics B et al. Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis. Scientific reports. 2021 Dec 22;11(1):24389.
• Jakobi T et al. Transcriptional Effects of Candidate COVID-19 Treatments on Cardiac Myocytes. Frontiers in cardiovascular medicine. 2022;9:844441.
• Rapedius M et al. There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments. Frontiers in molecular neuroscience. 2022;15:982316.
• Li W et al. Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration. Pharmaceuticals (Basel, Switzerland). 2022 Feb 12;15(2).
• Zhong R et al. A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells. International journal of molecular sciences. 2022 Jul 27;23(15).
• Fan X et al. Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. International journal of molecular sciences. 2022 Jul 31;23(15).
• Seibertz F et al. A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes. Communications biology. 2022 Sep 15;5(1):969.
• Li Y et al. Novel insights in the pathomechanism of Brugada syndrome and fever-related type 1 ECG changes in a preclinical study using human-induced pluripotent stem cell-derived cardiomyocytes. Clinical and translational medicine. 2023 Mar;13(3):e1130.
• Kermani F et al. Membrane remodelling triggers maturation of excitation-contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes. Basic research in cardiology. 2023 Mar 29;118(1):13.
• Seibertz F et al. Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes. Basic research in cardiology. 2023 Apr 5;118(1):14.
• Nakhaei-Rad S et al. Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues. Communications biology. 2023 Jun 21;6(1):657.
• Chowdhury A et al. Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome. EMBO molecular medicine. 2023 Sep 11;15(9):e17399.
• Xu Q et al. Esophageal Cancer-Related Gene-4 Contributes to Lipopolysaccharide-Induced Ion Channel Dysfunction in hiPSC-Derived Cardiomyocytes. Journal of inflammation research. 2024;17:10183-10197.
• Paasche A et al. Acute antiarrhythmic effects of SGLT2 inhibitors-dapagliflozin lowers the excitability of atrial cardiomyocytes. Basic research in cardiology. 2024 Feb;119(1):93-112.
• Schwenzer Niko et al. Nanoscale architecture and dynamics of Ca _V 1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy. . 2024-02-28.
• Knauer C et al. Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants. Molecular therapy. Nucleic acids. 2024 Mar 12;35(1):102123.
• Fischer D et al. An approach to evaluate the effect of inflammatory microvesicles on Ca(2+) handling in human-induced pluripotent stem cell-derived cardiomyocytes. Experimental biology and medicine (Maywood, N.J.). 2025;250:10461.
• Schwenzer N et al. Nanoscale architecture and dynamics of Ca(V)1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy. Journal of molecular and cellular cardiology plus. 2025 Dec;14:100490.

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