High quality clinical grade human embryonic stem cell lines derived from fresh discarded embryos
Summary
The present study, for the first time, reports the successful derivation of highest-quality clinical-grade hESC lines from fresh poor-quality surplus human embryos generated in a GMP-grade IVF laboratory. The availability of hESC lines of this status represents an important step towards more widespread application of regenerative medicine therapies.
| Authors | Ye J, Bates N, Soteriou D, Grady L, Edmond C, Ross A, Kerby A, Lewis PA, Adeniyi T, Wright R, Poulton KV, Lowe M, Kimber SJ, Brison DR |
|---|---|
| Journal | Stem cell research & therapy |
| Publication Date | 2017 Jun 5;8(1):128 |
| PubMed | 28583200 |
| PubMed Central | PMC5460457 |
| DOI | 10.1186/s13287-017-0561-y |